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LIPOPROTEINS, HDL
Descriptors Found:
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DeCS
Descriptor
English
:
Lipoproteins, HDL
Descriptor
Spanish
:
Lipoproteínas HDL
Descriptor
Portuguese
:
Lipoproteínas HDL
Synonyms
English
:
HDL Lipoproteins
Heavy Lipoproteins
High Density Lipoproteins
High-Density Lipoproteins
Lipoproteins, Heavy
Lipoproteins, High-Density
alpha Lipoproteins
alpha-1 Lipoprotein
alpha-Lipoproteins
Tree Number:
D10.532.432
D12.776.521.479
Definition
English
:
A class of
lipoproteins
of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL
lipoproteins
, synthesized in the liver without a lipid core, accumulate
cholesterol esters
from peripheral
tissues
and transport them to the liver for re-utilization or elimination from the body (the reverse
cholesterol
transport). Their major protein component is
APOLIPOPROTEIN A-I
. HDL also shuttle
APOLIPOPROTEINS C
and
APOLIPOPROTEINS E
to and from triglyceride-rich
lipoproteins
during their catabolism. HDL
plasma
level has been inversely correlated with the risk of
cardiovascular diseases.
Indexing Annotation
English
:
hyperalphalipoproteinemia =
LIPOPROTEINS
, HDL
/blood
(IM) +
HYPERLIPOPROTEINEMIAS
(IM); hypoalphalipoproteinemia =
LIPOPROTEINS
, HDL
/blood
(IM) +
HYPOLIPOPROTEINEMIAS
(IM); familial hypoalphalipoproteinemia =
TANGIER DISEASE
; /defic: consider also
HYPOLIPOPROTEINEMIAS
See Related
English
:
Tangier Disease
History Note
English
:
74(72)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
8249
Unique Identifier:
D008075
Occurrence in VHL
:
Similar:
DeCS